Publications from Nukina’ Lab since 2005

1. Wimmer VC, Harty RC, Richards KL, Phillips AM, Miyazaki H, Nukina N, et al. Sodium channel beta1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain. The Journal of comparative neurology. 2015;523(5):814-30.
2. Ogawa M, Shidara H, Oka K, Kurosawa M, Nukina N, Furukawa Y. Cysteine residues in Cu,Zn-superoxide dismutase are essential to toxicity in Caenorhabditis elegans model of amyotrophic lateral sclerosis. Biochemical and biophysical research communications. 2015;463(4):1196-202.
3. Matsumoto G, Shimogori T, Hattori N, Nukina N. TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation. Human molecular genetics. 2015;24(15):4429-42.
4. Kurosawa M, Matsumoto G, Sumikura H, Hatsuta H, Murayama S, Sakurai T, et al. Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases. Neuroscience research. 2015.
5. Kurosawa M, Matsumoto G, Kino Y, Okuno M, Kurosawa-Yamada M, Washizu C, et al. Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington’s model mice. Human molecular genetics. 2015;24(4):1092-105.
6. Kino Y, Washizu C, Kurosawa M, Yamada M, Miyazaki H, Akagi T, et al. FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis. Acta neuropathologica communications. 2015;3:24.
7. Kino Y, Washizu C, Kurosawa M, Oma Y, Hattori N, Ishiura S, et al. Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins. Human molecular genetics. 2015;24(3):740-56.
8. Inobe T, Nozaki M, Nukina N. Artificial regulation of p53 function by modulating its assembly. Biochemical and biophysical research communications. 2015;467(2):322-7.
9. Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS genetics. 2015;11(9):e1005503.
10. Yamanaka T, Wong HK, Tosaki A, Bauer PO, Wada K, Kurosawa M, et al. Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation. PloS one. 2014;9(4):e93891.
11. Yamanaka T, Tosaki A, Kurosawa M, Matsumoto G, Koike M, Uchiyama Y, et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nature communications. 2014;5:3354.
12. Shiba-Fukushima K, Arano T, Matsumoto G, Inoshita T, Yoshida S, Ishihama Y, et al. Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering. PLoS genetics. 2014;10(12):e1004861.
13. Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y. Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis. The Journal of biological chemistry. 2014;289(2):1192-202.
14. Miyazaki H, Oyama F, Inoue R, Aosaki T, Abe T, Kiyonari H, et al. Singular localization of sodium channel beta4 subunit in unmyelinated fibres and its role in the striatum. Nature communications. 2014;5:5525.
15. Maheshwari M, Bhutani S, Das A, Mukherjee R, Sharma A, Kino Y, et al. Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington’s disease. Human molecular genetics. 2014;23(10):2737-51.
16. Hamada K, Terauchi A, Nakamura K, Higo T, Nukina N, Matsumoto N, et al. Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(38):E3966-75.
17. Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, et al. Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Biochimica et biophysica acta. 2014;1842(9):1472-84.
18. Asada A, Yamazaki R, Kino Y, Saito T, Kimura T, Miyake M, et al. Cyclin-dependent kinase 5 phosphorylates and induces the degradation of ataxin-2. Neuroscience letters. 2014;563:112-7.
19. Yamanaka T, Tosaki A, Kurosawa M, Akimoto K, Hirose T, Ohno S, et al. Loss of aPKClambda in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains. PloS one. 2013;8(12):e84036.
20. Ikeda T, Kurosawa M, Morimoto C, Kitayama S, Nukina N. Multiple effects of repetitive transcranial magnetic stimulation on neuropsychiatric disorders. Biochemical and biophysical research communications. 2013;436(2):121-7.
21. Furukawa Y, Nukina N. Functional diversity of protein fibrillar aggregates from physiology to RNA granules to neurodegenerative diseases. Biochimica et biophysica acta. 2013;1832(8):1271-8.
22. Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N. Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis. FEBS letters. 2013;587(16):2500-5.
23. Nguyen HM, Miyazaki H, Hoshi N, Smith BJ, Nukina N, Goldin AL, et al. Modulation of voltage-gated K+ channels by the sodium channel beta1 subunit. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(45):18577-82.
24. Mitomi Y, Nomura T, Kurosawa M, Nukina N, Furukawa Y. Post-aggregation oxidation of mutant huntingtin controls the interactions between aggregates. The Journal of biological chemistry. 2012;287(41):34764-75.
25. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012;8(4):445-544.
26. Ding F, Furukawa Y, Nukina N, Dokholyan NV. Local unfolding of Cu, Zn superoxide dismutase monomer determines the morphology of fibrillar aggregates. Journal of molecular biology. 2012;421(4-5):548-60.
27. Bauer PO, Hudec R, Goswami A, Kurosawa M, Matsumoto G, Mikoshiba K, et al. ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT. Molecular neurodegeneration. 2012;7:43.
28. Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Molecular cell. 2011;44(2):279-89.
29. Kino Y, Washizu C, Aquilanti E, Okuno M, Kurosawa M, Yamada M, et al. Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations. Nucleic acids research. 2011;39(7):2781-98.
30. Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N. A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions. The Journal of biological chemistry. 2011;286(21):18664-72.
31. Furukawa Y, Kaneko K, Nukina N. Tau protein assembles into isoform- and disulfide-dependent polymorphic fibrils with distinct structural properties. The Journal of biological chemistry. 2011;286(31):27236-46.
32. Furukawa Y, Kaneko K, Nukina N. Molecular properties of TAR DNA binding protein-43 fragments are dependent upon its cleavage site. Biochimica et biophysica acta. 2011;1812(12):1577-83.
33. Doi H, Yoshida K, Yasuda T, Fukuda M, Fukuda Y, Morita H, et al. Exome sequencing reveals a homozygous SYT14 mutation in adult-onset, autosomal-recessive spinocerebellar ataxia with psychomotor retardation. American journal of human genetics. 2011;89(2):320-7.
34. Bauer PO, Hudec R, Ozaki S, Okuno M, Ebisui E, Mikoshiba K, et al. Genetic ablation and chemical inhibition of IP3R1 reduce mutant huntingtin aggregation. Biochemical and biophysical research communications. 2011;416(1-2):13-7.
35. Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, et al. Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction. Human molecular genetics. 2010;19(11):2099-112.
36. Yamanaka T, Nukina N. Transcription factor sequestration by polyglutamine proteins. Methods in molecular biology. 2010;648:215-29.
37. Tateishi T, Hokonohara T, Yamasaki R, Miura S, Kikuchi H, Iwaki A, et al. Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation. Acta neuropathologica. 2010;119(3):355-64.
38. Nishimura Y, Yalgin C, Akimoto S, Doumanis J, Sasajima R, Nukina N, et al. Selection of behaviors and segmental coordination during larval locomotion is disrupted by nuclear polyglutamine inclusions in a new Drosophila Huntington’s disease-like model. Journal of neurogenetics. 2010;24(4):194-206.
39. Li B, Hu Q, Wang H, Man N, Ren H, Wen L, et al. Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases. Cell death and differentiation. 2010;17(11):1773-84.
40. Higo T, Hamada K, Hisatsune C, Nukina N, Hashikawa T, Hattori M, et al. Mechanism of ER stress-induced brain damage by IP(3) receptor. Neuron. 2010;68(5):865-78.
41. Furukawa Y, Kaneko K, Yamanaka K, Nukina N. Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis. The Journal of biological chemistry. 2010;285(29):22221-31.
42. Doi H, Koyano S, Suzuki Y, Nukina N, Kuroiwa Y. The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases. Neuroscience research. 2010;66(1):131-3.
43. Brackenbury WJ, Calhoun JD, Chen C, Miyazaki H, Nukina N, Oyama F, et al. Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 2010;107(5):2283-8.
44. Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, et al. Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein. Nature biotechnology. 2010;28(3):256-63.
45. Tsutsui H, Shimizu H, Mizuno H, Nukina N, Furuta T, Miyawaki A. The E1 mechanism in photo-induced beta-elimination reactions for green-to-red conversion of fluorescent proteins. Chemistry & biology. 2009;16(11):1140-7.
46. Tateno M, Kato S, Sakurai T, Nukina N, Takahashi R, Araki T. Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. Human molecular genetics. 2009;18(5):942-55.
47. Remme CA, Scicluna BP, Verkerk AO, Amin AS, van Brunschot S, Beekman L, et al. Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy. Circulation research. 2009;104(11):1283-92.
48. Patino GA, Claes LR, Lopez-Santiago LF, Slat EA, Dondeti RS, Chen C, et al. A functional null mutation of SCN1B in a patient with Dravet syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009;29(34):10764-78.
49. Nekooki-Machida Y, Kurosawa M, Nukina N, Ito K, Oda T, Tanaka M. Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(24):9679-84.
50. Kino Y, Washizu C, Oma Y, Onishi H, Nezu Y, Sasagawa N, et al. MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1. Nucleic acids research. 2009;37(19):6477-90.
51. Iwata A, Nagashima Y, Matsumoto L, Suzuki T, Yamanaka T, Date H, et al. Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system. The Journal of biological chemistry. 2009;284(15):9796-803.
52. Ito H, Yoshimura N, Kurosawa M, Ishii S, Nukina N, Okazawa H. Knock-down of PQBP1 impairs anxiety-related cognition in mouse. Human molecular genetics. 2009;18(22):4239-54.
53. Godavarthi SK, Narender D, Mishra A, Goswami A, Rao SN, Nukina N, et al. Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction. Journal of neurochemistry. 2009;108(3):787-95.
54. Furukawa Y, Kaneko K, Matsumoto G, Kurosawa M, Nukina N. Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009;29(16):5153-62.
55. Doumanis J, Wada K, Kino Y, Moore AW, Nukina N. RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation. PloS one. 2009;4(9):e7275.
56. Chang WH, Tien CL, Chen TJ, Nukina N, Hsieh M. Decreased protein synthesis of Hsp27 associated with cellular toxicity in a cell model of Machado-Joseph disease. Neuroscience letters. 2009;454(2):152-6.
57. Bauer PO, Wong HK, Oyama F, Goswami A, Okuno M, Kino Y, et al. Inhibition of Rho kinases enhances the degradation of mutant huntingtin. The Journal of biological chemistry. 2009;284(19):13153-64.
58. Bauer PO, Nukina N. Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy. Autophagy. 2009;5(5):747-8.
59. Bauer PO, Nukina N. The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies. Journal of neurochemistry. 2009;110(6):1737-65.
60. Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, et al. Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. The EMBO journal. 2008;27(6):827-39.
61. Wong HK, Bauer PO, Kurosawa M, Goswami A, Washizu C, Machida Y, et al. Blocking acid-sensing ion channel 1 alleviates Huntington’s disease pathology via an ubiquitin-proteasome system-dependent mechanism. Human molecular genetics. 2008;17(20):3223-35.
62. Wong ES, Tan JM, Soong WE, Hussein K, Nukina N, Dawson VL, et al. Autophagy-mediated clearance of aggresomes is not a universal phenomenon. Human molecular genetics. 2008;17(16):2570-82.
63. Wang HQ, Imai Y, Inoue H, Kataoka A, Iita S, Nukina N, et al. Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss. Journal of neurochemistry. 2008;107(1):171-85.
64. Shimizu H, Tosaki A, Kaneko K, Hisano T, Sakurai T, Nukina N. Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production. Molecular and cellular biology. 2008;28(11):3663-71.
65. Sakurai T, Kaneko K, Okuno M, Wada K, Kashiyama T, Shimizu H, et al. Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing. The Journal of cell biology. 2008;183(2):339-52.
66. Mishra A, Dikshit P, Purkayastha S, Sharma J, Nukina N, Jana NR. E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity. The Journal of biological chemistry. 2008;283(12):7648-56.
67. Khan LA, Yamanaka T, Nukina N. Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans. Biochemical and biophysical research communications. 2008;368(3):729-35.
68. Kaminosono S, Saito T, Oyama F, Ohshima T, Asada A, Nagai Y, et al. Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008;28(35):8747-55.
69. Furukawa Y, Kaneko K, Yamanaka K, O’Halloran TV, Nukina N. Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis. The Journal of biological chemistry. 2008;283(35):24167-76.
70. Fujiwara M, Marusawa H, Wang HQ, Iwai A, Ikeuchi K, Imai Y, et al. Parkin as a tumor suppressor gene for hepatocellular carcinoma. Oncogene. 2008;27(46):6002-11.
71. Doi H, Okamura K, Bauer PO, Furukawa Y, Shimizu H, Kurosawa M, et al. RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells. The Journal of biological chemistry. 2008;283(10):6489-500.
72. Chen X, Tang TS, Tu H, Nelson O, Pook M, Hammer R, et al. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008;28(48):12713-24.
73. Zhang T, Jia N, Fei E, Wang P, Liao Z, Ding L, et al. Nurr1 is phosphorylated by ERK2 in vitro and its phosphorylation upregulates tyrosine hydroxylase expression in SH-SY5Y cells. Neuroscience letters. 2007;423(2):118-22.
74. Wang H, Jia N, Fei E, Wang Z, Liu C, Zhang T, et al. p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome. Journal of neurochemistry. 2007;101(6):1651-61.
75. Morishima-Kawashima M, Han X, Tanimura Y, Hamanaka H, Kobayashi M, Sakurai T, et al. Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains. Journal of neurochemistry. 2007;101(4):949-58.
76. Miyazaki H, Oyama F, Wong HK, Kaneko K, Sakurai T, Tamaoka A, et al. BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit. Biochemical and biophysical research communications. 2007;361(1):43-8.
77. Liu C, Fei E, Jia N, Wang H, Tao R, Iwata A, et al. Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis. The Journal of biological chemistry. 2007;282(19):14558-66.
78. Iida J, Ishizaki H, Okamoto-Tanaka M, Kawata A, Sumita K, Ohgake S, et al. Synaptic scaffolding molecule alpha is a scaffold to mediate N-methyl-D-aspartate receptor-dependent RhoA activation in dendrites. Molecular and cellular biology. 2007;27(12):4388-405.
79. Fei E, Jia N, Zhang T, Ma X, Wang H, Liu C, et al. Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3. Biochemical and biophysical research communications. 2007;357(2):487-92.
80. Chen C, Dickendesher TL, Oyama F, Miyazaki H, Nukina N, Isom LL. Floxed allele for conditional inactivation of the voltage-gated sodium channel beta1 subunit Scn1b. Genesis. 2007;45(9):547-53.
81. Urushitani M, Sik A, Sakurai T, Nukina N, Takahashi R, Julien JP. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nature neuroscience. 2006;9(1):108-18.
82. Oyama F, Miyazaki H, Sakamoto N, Becquet C, Machida Y, Kaneko K, et al. Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington’s disease transgenic mice. Journal of neurochemistry. 2006;98(2):518-29.
83. Mitsui K, Doi H, Nukina N. Proteomics of polyglutamine aggregates. Methods in enzymology. 2006;412:63-76.
84. Machida Y, Okada T, Kurosawa M, Oyama F, Ozawa K, Nukina N. rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse. Biochemical and biophysical research communications. 2006;343(1):190-7.
85. Khan LA, Bauer PO, Miyazaki H, Lindenberg KS, Landwehrmeyer BG, Nukina N. Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans. Journal of neurochemistry. 2006;98(2):576-87.
86. Goswami A, Dikshit P, Mishra A, Nukina N, Jana NR. Expression of expanded polyglutamine proteins suppresses the activation of transcription factor NFkappaB. The Journal of biological chemistry. 2006;281(48):37017-24.
87. Goswami A, Dikshit P, Mishra A, Mulherkar S, Nukina N, Jana NR. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction. Biochemical and biophysical research communications. 2006;342(1):184-90.
88. Dikshit P, Goswami A, Mishra A, Nukina N, Jana NR. Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction. Biochemical and biophysical research communications. 2006;342(4):1323-8.
89. Bennett EJ, Shaler T, Gonzalez-Zulueta M, Schulman HF, Iwata A, Riley BE, et al. Cellular mechanisms of protein quality control. Rinsho shinkeigaku = Clinical neurology. 2006;46(11):805.
90. Wong HK, Sakurai T, Oyama F, Kaneko K, Wada K, Miyazaki H, et al. beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase. The Journal of biological chemistry. 2005;280(24):23009-17.
91. Tsutsui H, Karasawa S, Shimizu H, Nukina N, Miyawaki A. Semi-rational engineering of a coral fluorescent protein into an efficient highlighter. EMBO reports. 2005;6(3):233-8.
92. Tanaka M, Machida Y, Nukina N. A novel therapeutic strategy for polyglutamine diseases by stabilizing aggregation-prone proteins with small molecules. Journal of molecular medicine. 2005;83(5):343-52.
93. Kotliarova S, Jana NR, Sakamoto N, Kurosawa M, Miyazaki H, Nekooki M, et al. Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates. Journal of neurochemistry. 2005;93(3):641-53.
94. Jana NR, Nukina N. BAG-1 associates with the polyglutamine-expanded huntingtin aggregates. Neuroscience letters. 2005;378(3):171-5.
95. Jana NR, Dikshit P, Goswami A, Kotliarova S, Murata S, Tanaka K, et al. Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes. The Journal of biological chemistry. 2005;280(12):11635-40.
96. Iwata A, Christianson JC, Bucci M, Ellerby LM, Nukina N, Forno LS, et al. Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. Proceedings of the National Academy of Sciences of the United States of America. 2005;102(37):13135-40.
97. Ikeda T, Kurosawa M, Uchikawa C, Kitayama S, Nukina N. Modulation of monoamine transporter expression and function by repetitive transcranial magnetic stimulation. Biochemical and biophysical research communications. 2005;327(1):218-24.
98. Chang WH, Cemal CK, Hsu YH, Kuo CL, Nukina N, Chang MH, et al. Dynamic expression of Hsp27 in the presence of mutant ataxin-3. Biochemical and biophysical research communications. 2005;336(1):258-67.
99. Bauer PO, Kotliarova SE, Matoska V, Musova Z, Hedvicakova P, Boday A, et al. Fluorescent multiplex PCR–fast method for autosomal dominant spinocerebellar ataxias screening. Genetika. 2005;41(6):830-7.